Biotransformation of (–)-Caryophyllene Oxide by Cell Suspension Culture of Catharanthus roseus
نویسندگان
چکیده
Catharanthus roseus cell suspension cultures were employed for the biotransformation of (–)-caryophyllene oxide (1), and four metabolites, 15-hydroxycaryophyllene oxide (2), 4β ,5αdihydroxycaryophyll-8(13)-ene (3), 2β -hydroxycaryophyllene oxide (4), and 2-hydroxy-4,5epoxycaryophyllan-13-ol (5) were obtained. Metabolites 4 and 5 were found to be new compounds, and their structures were deduced by different spectroscopic techniques.
منابع مشابه
Callus Induction and Cell Suspension Culture Production of Catharanthus Roseus for Biotransformation Studies of (–)- Caryophyllene Oxide
For biotransformational studies, Callus of Catharanthus roseus was produced from young shoot tip on Murashige & Skoog medium supplemented with 1.5 mg/litre 2, 4-D and 0.5 mg/litre Kin, solidified by 8 g/litre agar at 25±1°C under complete darkness. The cultures were maintained on the same medium at 25±1 °C in the dark by subculturing after every four weeks. Suspension culture of the plant was p...
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